Journal: ACS Nano

Article Title: Topology Outweighs Stiffness: Self-Reinforced Cell Mechanotransduction via Multiaxial Curvature Engineering of Ultrasoft Hydrogels

doi: 10.1021/acsnano.5c19367

Figure Lengend Snippet: Multiaxial curvature engineering on 3d ultrasoft microgels for stem cell mechanosensing and tissue engineering applications. (a) Schematic illustrating the microfluidic technique for generating ultrasoft microgels with a multiaxial curvature via the SICE process. (b) Fluorescence microscopy images comparing the surface morphology of smooth and SICE-treated multiaxial curvature microgels across different sizes. Scale bar: 100 μm. (c) Color map showcasing the curvature features of 3D microgels with varied curvature conditions. The scale bars indicate 20 μm, 50 μm, and 100 μm from left to right. (d,e) Quantitative analysis of the size ( N = 30–50), stiffness ( N = 10), and curvature of 3D microgels ( N = 3). (f) Immunofluorescence staining of F-actin (red) and nuclei (blue) in hMSCs cultured on 3D microgels with different curvature conditions. (g) Osteogenic differentiation of hMSCs on 3D microgels with varying curvature conditions. Cells were cultured in osteogenic medium for 7 days and stained with alkaline phosphatase (ALP) dye to indicate early osteogenic differentiation. Scale bar: 500 μm. (h–i) Quantification of hMSCs’ spreading area ( N = 15–20, three technical replicates) and osteogenic differentiation (based on ALP activity) on 3D microgels ( N = 10–15, three technical replicates).

Article Snippet: The designed microfluidic chip is illustrated in Figure S14 and is fabricated using a 3D printing process (Form 3B+, Formlabs).

Techniques: Fluorescence, Microscopy, Immunofluorescence, Staining, Cell Culture, Activity Assay

Journal: BMC Oral Health

Article Title: Mechanical and optical effects of post-curing time and device type in two 3D-printed resin systems

doi: 10.1186/s12903-025-06813-6

Figure Lengend Snippet: 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED)

Article Snippet: Fig. 1 Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer Fig. 2 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED) Fig. 3 3D surface profile analysis of samples produced on DLP type 3d printer (Asiga MAX UV, Asiga, Australia) (A: UV LED, B: Blue LED) When the microhardness values were examined after the samples produced in 3D printers were polymerized in 10, 20, 40 and 60 min in blue LED and UV LED devices, a statistically significant difference was observed according to the polymerization time ( p < 0.05).

Techniques: Produced

Journal: BMC Oral Health

Article Title: Mechanical and optical effects of post-curing time and device type in two 3D-printed resin systems

doi: 10.1186/s12903-025-06813-6

Figure Lengend Snippet: Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer

Article Snippet: Fig. 1 Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer Fig. 2 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED) Fig. 3 3D surface profile analysis of samples produced on DLP type 3d printer (Asiga MAX UV, Asiga, Australia) (A: UV LED, B: Blue LED) When the microhardness values were examined after the samples produced in 3D printers were polymerized in 10, 20, 40 and 60 min in blue LED and UV LED devices, a statistically significant difference was observed according to the polymerization time ( p < 0.05).

Techniques: Produced

Journal: BMC Oral Health

Article Title: Mechanical and optical effects of post-curing time and device type in two 3D-printed resin systems

doi: 10.1186/s12903-025-06813-6

Figure Lengend Snippet: Initial and post thermal cycling microhardness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer

Article Snippet: Fig. 1 Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer Fig. 2 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED) Fig. 3 3D surface profile analysis of samples produced on DLP type 3d printer (Asiga MAX UV, Asiga, Australia) (A: UV LED, B: Blue LED) When the microhardness values were examined after the samples produced in 3D printers were polymerized in 10, 20, 40 and 60 min in blue LED and UV LED devices, a statistically significant difference was observed according to the polymerization time ( p < 0.05).

Techniques: Produced

Journal: BMC Oral Health

Article Title: Mechanical and optical effects of post-curing time and device type in two 3D-printed resin systems

doi: 10.1186/s12903-025-06813-6

Figure Lengend Snippet: Color change (∆E 00 ) values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer

Article Snippet: Fig. 1 Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer Fig. 2 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED) Fig. 3 3D surface profile analysis of samples produced on DLP type 3d printer (Asiga MAX UV, Asiga, Australia) (A: UV LED, B: Blue LED) When the microhardness values were examined after the samples produced in 3D printers were polymerized in 10, 20, 40 and 60 min in blue LED and UV LED devices, a statistically significant difference was observed according to the polymerization time ( p < 0.05).

Techniques: Produced

Journal: BMC Oral Health

Article Title: Mechanical and optical effects of post-curing time and device type in two 3D-printed resin systems

doi: 10.1186/s12903-025-06813-6

Figure Lengend Snippet: Whiteness index values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer

Article Snippet: Fig. 1 Initial and post thermal cycling surface roughness values of samples produced by applying different curing devices and post polymerization time in DLP and SLA type 3D printer Fig. 2 3D surface profile analysis of samples produced on SLA type 3d printer (Formlab 3B+, Formlabs, USA) (A: UV LED, B: Blue LED) Fig. 3 3D surface profile analysis of samples produced on DLP type 3d printer (Asiga MAX UV, Asiga, Australia) (A: UV LED, B: Blue LED) When the microhardness values were examined after the samples produced in 3D printers were polymerized in 10, 20, 40 and 60 min in blue LED and UV LED devices, a statistically significant difference was observed according to the polymerization time ( p < 0.05).

Techniques: Produced